Research at the Unit

 

Research Sections

 

The scientific work of the unit is divided into three sections:

 

Biomedical Systems Analysis

Section Head: Professor Richard Baldock

 

Chromosomes and Gene Expression

Section Head: Professor Wendy Bickmore

 

Medical and Developmental Genetics

Joint Section Heads: Professor David FitzPatrick, Professor Ian Jackson

 

The unit takes an integrative approach to its work and a number of the projects span more than one section and across the MRC Institute of Genetics and Molecular Medicine to bring together the scientific interests and skills of staff. Scientists come from a range of disciplines and use a broad range of approaches to tackle projects which cover the spectrum of basic through to clinical research.


 

Group Leaders


Dr Ian Adams

Dr Ian Adams

germ cell development, spermatogenesis, oogenesis, meiosis

Professor Richard Baldock

Professor
Richard
Baldock

mouse developmental atlas, gene-expression atlases, bioinformatics

Professor Wendy Bickmore

Professor Wendy Bickmore

genome organisation, chromatin, nucleus

Macrophages bursting into the lumen of a cancerous bile duct.

Dr Luke Boulter

IGMM Chancellor's Fellowship

Liver, Regeneration, Homeostasis

Dr Javier Caceres

Professor Javier Caceres

RNA processing in eukaryotes, alternative splicing, microRNAs

Dr Julia Dorin

Dr Julia Dorin

host defence peptides, inflammatory modulation, models of human disease

Professor Malcolm Dunlop

Professor Malcolm Dunlop

colorectal cancer, genetic susceptibility, prevention

Dr David FitzPatrick

Professor David FitzPatrick

malformation, cleft palate, anophthalmia

Professor Nick Gilbert

Professor Nick Gilbert

chromatin, genome stability, transcription

Professor Chris Haley

Professor Chris Haley

complex traits, quantitative genetics

Professor Nick Hastie

Professor Nick Hastie

developmental genetics, pediatric cancer, tissue maintenance

Dr Caroline Hayward

Dr Caroline Hayward

human genetics, genotype analysis and quantitative traits

Professor Bob Hill

Professor Robert Hill

limb development, left right asymmetry, sonic hedgehog, long range regulation

Dr Toby Hurd

Dr Toby Hurd

IGMM Chancellor's Fellowship

cilia, kidney, retina

Dr Andrew Jackson

Professor Andrew Jackson

genetic disorders of brain size, nucleic-acid mediated inflammation

Professor Ian Jackson

Professor Ian Jackson

mouse genetics, melanocytes, mouse genomics

Dr Sasha Kagansky

Dr Sasha Kagansky

IGMM Chancellor's Fellowship

epigenetics, chromatin

Dr Greg Kudla

Dr Grzegorz Kudla

gene expression, codon usage

Dr Joe Marsh

Dr Joe Marsh

IGMM Chancellor's Fellowship

protein complexes, mutations, regulation

Dr Richard Meehan

Professor Richard Meehan

epigenetics of development, DNA methyltransferases, methyl-CpG binding proteins

Dr Pleasantine Mill

Dr Pleasantine Mill

mouse models, developmental genetics, cilia and centrosomes

Dr Ian Overton

Dr Ian Overton

data integration, network biology, systems medicine

Dr Elizabeth Patton

Dr Elizabeth Patton

melanocyte, melanoma, zebrafish, MAPK-signaling developmental disease

Dr Colin Semple

Dr Colin Semple

bioinformatics, regulatory genomics

Dr Duncan Sproul

Dr Duncan Sproul

epigenetics, cancer, bioinformatics

Dr Martin Taylor

Dr Martin Taylor

mutation, selection, regulation, disease

Dr Veronique Vitart

Dr Veronique Vitart

genetics, quantitative traits, isolate populations

 

Dr Andrew Wood

Dr Andrew Wood

IGMM Chancellor's Fellowship

chromosomal instability, haematopoiesis, genome editing