Human genome variants associated with intellectual disability drive different patterns of gene expression (green and red) in transgenic zebrafish.

The Medical Research Council Human Genetics Unit, a partner in the MRC Institute of Genetics and Molecular Medicine at The University of Edinburgh, is at the forefront of research into human genetics.

Its mission is to understand the role of genes and the genome in normal development and physiology and how changes in genome sequence impact on human health and disease. The Unit's programmes of work cover the themes of rare and common disease genetics, gene regulation and genome stability.

Latest News

Genetic barcode could pave way to bespoke liver cancer therapies Genetic barcode could pave way to bespoke liver cancer therapies

Researchers at the MRC Human Genetics Unit have identified a biological barcode in mouse cells that could help explain how liver cancers develop in people...Read more



Flagging up new gene switches Flagging up new gene switches

The human genome contains barely more protein-coding genes than that of a fruit fly. The more complex development and behaviour of mammals lies, not in the number of their genes, but in how those genes are controlled...Read more



Dr Andrew Wood awarded 2017 Balfour LectureDr Andrew Wood awarded 2017 Balfour Lecture

The Genetics Society has announced that the 2017 Balfour Lecture will be awarded to Dr Andrew Wood a Sir Henry Dale Fellow and Chancellor’s Fellow in the MRC Human Genetics Unit...Read more


Yeast study charts survival impact of genetic mutationsYeast study charts survival impact of genetic mutations

Scientists from the MRC Human Genetics Unit have mapped how thousands of genetic mutations can affect a cell’s chances of survival...Read more



The MRC Human Genetics Unit (HGU) at The University of Edinburgh is funded by the Medical Research Council (MRC), a publicly-funded organisation dedicated to improving health by supporting research across the entire spectrum of medical sciences.





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